AZITHROMYCIN OVER THE COUNTER
What is Azithromycin used for?
Azithromycin is a macrolide antibiotic subgroup drug with a wide spectrum of action. In highly concentrated foci of inflammation has a bactericidal effect.
It is used to treat gram-positive cocci, gram-negative bacteria, certain types of anaerobic microorganisms, as well as Ureaplasma urealyticum, Clamydia trachomatis, Borrelia burgdoferi, Mycoplasma pneumoniae, Treponema pallidum. With respect to gram-positive bacteria that are resistant to erythromycin preparations, Azithromycin is inactive.
Azithromycin and alcohol
Can you drink alcohol while taking azithromycin?
People who are treated with azithromycin should refrain from drinking alcoholic beverages. First of all, alcohol affects the pharmacokinetics of the drug. Alcohol consumption simply worsens the absorption of the drug and its accumulation in the tissues. This means that the therapeutic effect will be less pronounced. That is, the treatment of the disease can be significantly delayed, or even lead to the emergence of various complications.
The instructions for the drug indicated that azithromycin is contraindicated for people suffering from severe liver disease. In this case, the liver can not fully perform the function of neutralization.
Azithromycin and pregnancy
The need for antibiotics during pregnancy causes fear and anxiety in expectant mothers: they can provoke allergic reactions, disrupt the microflora and have a toxic effect on the woman’s body. What will be the impact of drugs on the body of a little man in the tummy, to predict certainly not work. But in some situations, antibiotics are indispensable. Most often, pregnant women are prescribed Azithromycin.
Azithromycin during pregnancy may be prescribed to treat the following diseases:
- respiratory diseases, including pneumonia and bronchitis;
- nasopharyngeal diseases, including tonsillitis, pharyngitis;
- diseases of the gastrointestinal tract;
- dermatological diseases such as dermatosis,
erythema and erysipelas;
- urogenital infections;
- pathological processes in the kidneys, for example, pyelonephritis.
The most optimal period for taking medications, including antibiotics, is the second trimester. At this stage, the placental barrier has formed completely, and all the vital organs of the child have already been laid. Taking Azithromycin during pregnancy in the II trimester may be beneficial, exceeding the risk.
Of course, antibiotics for a pregnant woman are a potential threat. But some infectious diseases without timely treatment can have fatal consequences for both mother and baby. For example, untreated chlamydia can lead to cessation of fetal development and its death. Because of the infection, the child receives less oxygen and nutrients. Azithromycin is active against Chlamydia trachomatis, the causative agent of chlamydia. It can also be used for other urogenital infections, including syphilis caused by treponema pallus and mycoplasmosis.
In the last weeks of the term Azithromycin is not prescribed for pregnant women, since the drug substances are able to penetrate into breast milk and accumulate in it. Subsequently, during lactation, they will be transferred to the crumbs. If you can not do without the use of Azithromycin, breastfeeding is recommended to begin after discontinuation of the drug.
Antacids (aluminum and magnesium), ethanol and food slow down and reduce absorption. When co-administered with warfarin and azithromycin (in usual doses), there is no change in the prothrombin time, however, given that the interaction of macrolides and warfarin may increase the anticoagulant effect, patients need careful control of prothrombin time. Digoxin: increasing the concentration of digoxin. Ergotamine and dihydroergotamine: increased toxic effects (vasospasm, dysesthesia). Triazolam: reduced clearance and increased pharmacological action of triazolane. Slows down the use of , theophylline and others. Xanthine derivatives) – due to inhibition of microsomal oxidation in hepatocytes by azithromycin). Lincosamines impair efficacy, tetracycline and chloramphenicol increase. Pharmaceutical incompatible with heparin.
The drug is prohibited to use:
- with increased sensitivity to antibiotic macrolide group;
- with pathologies of the liver and kidneys;
- children under 12 years old and weighing less than 45 kg;
- during breastfeeding.
Also Azithromycin is not taken together with ergotamine and dihydroergotamine.
Azithromycin for sinus infection
Using azithromycin for sinus can completely get rid of the disease within a few days.
The drug is rapidly absorbed from the gastrointestinal tract and enters the respiratory tract, maxillary sinuses and other organs and tissues. Eating reduces the absorption of the drug.
The long half-life allows you to take azithromycin once a day.
Therapeutic drug concentration is maintained in the area of inflammation for several days after the last use of the pill. This property makes it possible to drink short three- or five-day antibiotic courses.
The drug is metabolized in the liver and excreted through bile and partially urine in unchanged form.
How long does it take for azithromycin to work for sinus infection?
The total duration of treatment of sinus infection with Azithromycin is from one to three weeks, depending on the severity of the disease.
Azithromycin dosage for sinus infection
Azithromycin is used to eliminate the inflammatory processes of the sinuses. It is able to concentrate in the focus of the disease and perfectly penetrates the respiratory organs. These properties served as the basis for drawing up the following treatment regimens with Azithromycin for antritis:
- adults take 500 mg on the first day of the disease, then either 500 mg three days each, or 250 mg each, from the second to the fifth day;
- children are prescribed a suspension: for the calculation they take 10 mg per 1 kg of weight, also once a day, in a similar way the treatment lasts 3 days;
- There is a scheme in which the suspension from the second day is used at 5 mg / kg for 4 days.
- The total dosage for children for the entire course is 30 mg / kg.
Azithromycin for pneumonia
Inflammation of the lungs is the most common cause of death in the world from infections. Every year, millions of people suffer this dangerous disease, so the correct selection of antibacterial drugs is still relevant. The choice of drugs for the treatment of pneumonia is carried out based on many factors. It is necessary to consider the sensitivity of the pathogen, the pharmacokinetics of the drug, contraindications and possible side effects. An important role in the choice of medication plays a method of use and frequency of treatment. Azithromycin in pneumonia often becomes the drug of choice No. 1, since this antibiotic has a detrimental effect on many pathogens, and it is necessary to take it only once a day.
Azithromycin dosage for pneumonia
The instructions for use of Azithromycin for pneumonia indicate that the drug should be taken in such dosages:
- Children over 12 years old and adults drink 1 capsule that contains 500 mg of the active substance, 1 time per day. The duration of treatment is most often 3 days.
- Children from 6 to 12 years old take 1 capsule, which contains 250 mg of the active substance, only once a day.
- Children up to 6 years, it is advisable to appoint a suspension. The dosage is calculated by the attending physician individually, depending on the age of the small patient.
The guide to the drug says that the interval between doses of the antibiotic should be about a day. In this case, a constantly high concentration of the drug is maintained in the blood.
In case of pneumonia, azithromycin is used with great caution in patients with chronic liver diseases, and hepatitis and severe hepatic insufficiency may develop. If there are signs of abnormal liver function, which are manifested by jaundice, darkening of urine and a tendency to bleeding, the therapy with an antibacterial drug is stopped and the patient is examined.
Azithromycin for chlamydia
For effective treatment of chlamydia, several dozens of drugs are used, and everyone can show positive results. In the treatment of chlamydia, all drugs are divided into several main groups, such as fluoroquinolones, tetracyclines, macrolides.
As for the drug itself, which can be considered a leader in the treatment of chlamydia, doctors recommend azithromycin.
Therapy of this disease should take into account not only the need to exclude the spread of chlamydia, that is, its maximum treatment, but also the exclusion of complications.
Azithromycin (a subclass of azalides) has practically made a revolution in the treatment of chlamydial infection. It is one of the most widely studied antibiotics for chlamydia, its effectiveness reaches 96%.
Azithromycin is especially effective in chronic persistent genital chlamydia.
The advantage of Azithromycin is that it works after taking a single dose. But the patient will have to wait seven days after the completion of treatment before you can have sex again.
How much azithromycin is needed to cure chlamydia?
Azithromycin for chlamydia (treatment regimen is selected individually by a doctor). To determine the required dosage can be by blood analysis. Azithromycin is used in the treatment of chronic or mutating chlamydia.
Initial treatment and exacerbation treatment regimen
Azithromycin treatment involves the development of an individual regimen, which depends on the stage of the disease, the presence of exacerbation and comorbidities. Therefore, the doctor prescribes tests that are designed to help determine the correct dosage of the drug.
If less than three months have passed since the infection and there are no symptoms of the acute form, azithromycin is taken one time two hours before meals and together with the immunomodulators.
With the exacerbation of the condition at the initial stage, the treatment regimen changes. The drug is drunk once for at least seven days and combined with drugs that restore the intestinal microflora and hepatoprotectors.
The total dosage of the antibiotic at the initial stage of chlamydia usually does not exceed 3 grams of the substance. But basically, the amount of azithromycin taken varies based on many factors. For example, if a couple undergoes treatment, the concentration of the drug in a man may differ from the dosage of the woman.
The treatment of chronic chlamydia
Therapy of the chronic form of chlamydia requires a long time and its effectiveness is possible only if you strictly follow the recommendations of the doctor.
The course of treatment with azithromycin is from two to three weeks. Intravenous drug is introduced, it allows you to increase its effectiveness and reduce the burden on the liver and heart. In parallel, it is necessary to carry out strengthening therapy with hepatoprotectors and cardioprotectors, usually they are prescribed in the form of injections.
For the treatment of chronic forms of the disease, the following rules must be observed:
- Take azithromycin at the same time. This will keep the concentration in the cells at the required level.
- Do not skip or stop taking the medication if no similar replacement drugs are prescribed. Interruption of treatment may form chlamydia resistance to the antibiotic and in the next course of treatment it will be ineffective.
- Reception aziromycin carried out only on the recommendation of a doctor. Following the course of treatment according to the instructions can lead to side effects or a latent form.
- Both partners should be treated. Sexual rest for them is registered until confirmation of complete recovery.
- During the course of treatment it is necessary to eliminate the use of alcohol. Otherwise, the absorption of the drug decreases.
Azithromycin for bronchitis
A number of antibiotics, which are most often chosen for the treatment of acute bronchitis of a bacterial nature, include macrolides, a prominent representative of which is Azithromycin. This drug fully blocks the processes of protein synthesis, without which the construction of microbial RNA is impossible.
Azithromycin is active for most pathogens, including anaerobes and aerobes.
Before using Azithromycin for bronchitis, it must be borne in mind that this drug does not affect not only the viruses, but also the causative agents of whooping cough and paracoclusum – such bacteria are called Bordetella. This fact must be taken into account if this antibiotic is prescribed to children who do not have immunity (not immunized) against whooping cough.
Azithromycin is indicated as a single agent in acute bronchitis or bronchiolitis of microbial origin.
In the acute period of chronic bronchitis, Azithromycin, which is active relative to the hemophilic bacilli, may become an alternative antibiotic.
Azithromycin in acute bronchitis is never prescribed from the first hours or days from the onset of the disease. An antibiotic is used only if there is an increased risk of complications – for example, the addition of a purulent infection.
Azithromycin in chronic bronchitis can indeed be effective: in the chronic course, penicillin or macrolide drugs are considered to be the antibiotics of choice. In severe form of the disease Azithromycin is used in injections, in mild cases it is enough to use tablets.
Azithromycin for obstructive bronchitis is used only after confirming the presence of a bacterial infection, because the main treatment for obstruction should be aimed at expanding the bronchi, lowering the viscosity of sputum and removing it from the airways. If an antibacterial agent is needed, the choice is made between aminopenicillin, fluoroquinolone and macrolide antibiotics: therefore, doctors often stop on Azithromycin.
Azithromycin dosage for bronchitis
Azithromycin for bronchitis can be prescribed to both adult patients and children weighing from 45 kg. The drug is taken orally, 60 minutes before a meal, or two hours later, daily, once a day.
As a rule, with bronchitis Azithromycin is taken according to this scheme:
- first day – 500 mg of antibiotic;
- from second to fifth day – 250 mg.
A short course of Azithromycin is also possible: for three days, 500 mg. The total amount of antibiotic per course is 1500 mg.
For elderly patients, as well as for persons suffering from mild failure of renal function, it is not necessary to adjust the amount of the drug.
How long does it take for azithromycin to work for bronchitis?
The duration of Azithromycin for bronchitis depends on the regimen prescribed by the doctor. Standardly, doctors use two treatment regimens for five days or three days. Longer reception is undesirable: the need for it is evaluated by the doctor individually.
Azithromycin for throat infection
Azithromycin is prescribed for chronic and purulent tonsillitis. It reduces inflammation and restores respiratory function, lowers temperature, eliminates sore throat and weakness.
When purulent lesion of the tonsils Azithromycin removes white plaque, helps clean their surfaces. It concentrates in places where inflammation is present. The effectiveness of the drug due to the fact that its effect continues for a week after taking the last dose.
Azithromycin in sore throat has certain advantages over other antibiotics. The main thing is the shorter duration of the treatment course. All drugs for purulent tonsillitis should be taken for 10 days or longer. Azithromycin is an exception. In order to eliminate the disease, 5-day therapy is enough. All symptoms that bring discomfort and reduce the quality of life are eliminated in a shorter time.
Another advantage of Azithromycin is its relative safety and less toxic compared to other antibiotics. The drug is well tolerated by most patients, is prescribed for the treatment of adults and children.
Azithromycin dosage for throat infection
The required amount of the drug is calculated based on the patient’s age:
- Azithromycin is not recommended from birth to 6 months. Antibiotics are prescribed only in severe cases and under constant medical supervision.
- From 6 months to 12 years, the drug is allowed to be used in the form of a suspension. The volume of a single dose depends on body weight (5 ml per 1 kg). Enough 1 medication per day, the course of treatment is not less than 3 days.
- From 12 years old (body weight – more than 45 kg), capsules are used. Single dose – 1 pc. (500 mg), 1 capsule per day, the course of treatment is 3 days.
Azithromycin for sore throat should be taken separately from food: 2 hours before or after, as food worsens the absorption of the drug into the blood. It is best to adhere to the regime, drink medicine at the same time every day. If the next reception is missed, then you need to take Azithromycin as soon as possible. The next capsule (dose of suspension) – in a day.
Azithromycin for ear infection
According to doctors, the inflammatory process occurring in the ear, is best treated with antibiotics from the class of “macrolides.” Azithromycin belongs to this group of drugs. Medicinal components are incorporated into the structure of pathogenic cells, destroying intracellular membranes.
Azithromycin is a semi-synthetic antibiotic that has a wide spectrum of action. Embedding in the structure of bacteria, inhibits protein synthesis and prevents further reproduction of pathogenic microorganisms. Available in the form of capsules, tablets, powder for suspension. Children, as a rule, when otitis is prescribed suspension.
Most often for otitis media, azithromycin is prescribed in the form of capsules.
Application depends on the meal: it is recommended to use one hour before meals or two hours later It is best to take at the same time, with a time interval of 24 hours. The standard regimen of azithromycin for otitis in adults and children consists of a single application for 3-5 days. Wash down with plenty of water. The required dosage must be prescribed by the attending physician.
As for children, the daily rate is calculated according to the following formula: 10 mg per 1 kg of body weight of the child. The permissible dose is divided into two doses. The standard course of treatment is 3 days.
Where can i buy azithromycin over the counter?
In our med-empire.net online pharmacy a large list of antibiotics including Azithromycin. All medicines are sold over the counter.